17 Mar Do Bioidentical Hormones Increase The Risk Of Stroke?

Bioidentical Hormones And Stroke Risk

Hormone replacement therapy (HRT) is a common treatment for menopausal symptoms and other hormone-related conditions. Bioidentical hormones are a form of HRT that uses hormones that are identical to the ones naturally produced by the body. Bioidentical hormones have been touted as a safer alternative to traditional HRT. However, there is still some debate about their safety. In particular, there is concern about whether bioidentical hormones increase the risk of stroke. In this article, we will explore the evidence for and against this claim.

What Are Bioidentical Hormones?

Bioidentical hormones are synthetic versions of hormones that are identical to those naturally produced by the body. They are derived from plant sources such as yams or soybeans and can be customised to match each individual’s unique hormone profile. Bioidentical hormones are often used in HRT to replace declining levels of oestrogen and progesterone in menopausal women. Bioidentical hormones are available in a variety of forms, including pills, creams, gels, and lozenges.

What Is the Evidence for an Increased Risk of Stroke?

There is concern about the potential link between bioidentical hormones and stroke. This stems from the fact that some studies have found that HRT increases the risk of stroke.

However, it is important to note that not all studies have found a link between HRT and stroke. The risks associated with HRT may depend on a variety of factors, including the type of hormone used, the dose, and the duration of treatment.

Despite the similarities between bioidentical hormones and HRT, there is currently limited research on the specific risks associated with bioidentical hormone therapy.

There is some evidence that suggests bioidentical hormones may increase the risk of stroke. A study published in 2016 found that women who took bioidentical oestrogen had an increased risk of stroke compared to those who did not take any hormone therapy at all. The authors concluded that “bioidentical oestrogen may be associated with an increased risk of stroke compared with no hormone therapy”.

However, it should be noted that this study was based on observational data and did not include any randomised controlled trials (RCTs). As such, it is possible that other factors such as lifestyle or medical history could have influenced the results. Additionally, it should be noted that this study only looked at one type of bioidentical hormone (oestrogen). It did not examine other types such as progesterone or testosterone.

What Is the Evidence Against an Increased Risk of Stroke?

Although there is some evidence suggesting a link between bioidentical hormones and an increased risk of stroke, there is also evidence suggesting otherwise. A systematic review published in 2017 examined 10 studies on the subject and concluded that “there was no significant association between use of bioidentical hormones and risk for stroke”. The authors also noted that most studies had small sample sizes which could have affected their results.

Additionally, another systematic review published in 2018 found no significant association between bioidentical hormone use and stroke risk compared with non-hormonal treatments such as lifestyle modifications or antidepressants. This review included both observational studies and RCTs. This suggests its findings may be more reliable than those from previous reviews which only included observational data.

Conclusion

Overall, there is some evidence suggesting a link between bioidentical hormone use and an increased risk of stroke. However, it is far from conclusive at this point in time. More research needs to be done before any definitive conclusions can be drawn about their safety. In the meantime, for individuals considering using bioidentical hormones, it is essential to consult with a doctor or BHRT Clinic. They will help you make an informed decision about whether they are right for you.

If you think you have a hormonal imbalance and are interested in bioidentical hormone replacement therapy please contact us at The Hormone Clinic or book an appointment with us today. We would be delighted to help you and get you on the road to feeling well again.